Recent advances in treatment for narcolepsy

An improved understanding of the causes of narcolepsy has led to an increase in the number of available pharmacological treatments for the sleep disorder, which has recently been reclassified into Narcolepsy Type 1 (NT1) and Narcolepsy Type 2 (NT2). Much more is known about the pathophysiology of NT1, with hypocretin/orexin (ORX) neurons being lost through what is thought to be an autoimmune process. This review article gives an overview of the newest pharmacological treatments for narcolepsy, including some new immune-based therapies.


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